GUIDELINES

GUIDELINESV ersion 2019 EnglishGUIDELINESV ersion 2021 EnglishEACS EuropeanAIDS Clinical Society1 EACS GUIDELINES of Contents Introduction to EACS GUIDELINES 20213 Summary of Changes from to Members5 Governing Board Members5 Abbreviations6 Part IAssessment of PLWH at Initial & Subsequent Visits7 Part IIART of PLWH10 Assessing PLWH's Readiness to Start and Maintain ART 10 Recommendations for Initiation of ART in PLWH with Chronic Infection without prior ART Exposure 12 Initial Combination Regimen for ART-na ve Adult PLWH 13 Primary HIV Infection (PHI)15 Switch Strategies for Virologically Suppressed Persons16 Virological Failure17 Treatment of Pregnant Women Living with HIV or Women Considering Pregnancy18 ART in TB/HIV Co-infection20 Post-exposure Prophylaxis (PEP) 22 Pre-exposure Prophylaxis (PrEP)23 Adverse Effects of ARVs and Drug Classes 24 Part IIIDrug-drug Interactions and Other Prescribing Issues in PLWH26 Drug-drug Interactions between ARVs and Non-ARVs27 Drug-drug Interactions between Analgesics and ARVs29 Drug-drug Interactions between Anticoagulants/Antiplatelet Agents and ARVs30 Drug-drug Interactions between Antidepressants and ARVs31 Drug-drug Interactions between Antihypertensives and ARVs32 Drug-drug Interactions between Anti-malarial Drugs and ARVs34 Drug-drug Interactions between Anti-tuberculosis Drugs and ARVs35 Drug-drug Interactions between Anxiolytics and ARVs36 Drug-drug Intera

Injury (HRS-AKI) 83 Dose Adjustment of ARVs for Impaired Hepatic Function 84 Lipodystrophy and Obesity: Prevention and Management 85 Hyperlactataemia and Lactic Acidosis: Diagnosis, Prevention and Management 87 Travel 88 Drug-drug Interactions between Anti-malarial Drugs and ARVs 89 Vaccination 90 Sexual and Reproductive Health of PLWH 91

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