Transcription of Guidelines for cryoprecipitate transfusion
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Guidelines for cryoprecipitate transfusion
VOL. 49 NO. 8, OCTOBER2007BC MEDICAL JOURNAL441 ABSTRACT: The literature showsthere is often inappropriate use of blood products, including cryo -precipitate plasma, because of in -adequate education of for cryoprecipitate trans-fusion have been developed by theTransfusion Medicine Advisory Groupof British Columbia to educate clini-cians and address transfusion prac-tices in the province. These guide-lines are based on a MEDLINE search and consultation with hema -to pathologists and clinicians. At pre-sent, transfusion of cryoprecipitateis indicated for hypofibrinogen emia/dysfibrinogenemia, von Willebranddisease, hemophilia A, factor XIII deficiency, and management ofbleeding related to thrombolytictherapy.
tative deficiency, as is seen in massive transfusion or disseminated intravascu-lar coagulation (DIC). Transfusion ther-Guidelines for cryoprecipitate transfusion apy with either frozen plasma (FP) or cryoprecipitate is usually indicated if fibrinogen levels are less than 1.0 g/L, and bleeding is present, although clin-
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