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GUIDELINES FOR MANAGEMENT OF ADVERSE …

NATIONAL 111I01502 GUIDELINES FOR MANAGEMENT OF ADVERSE transfusion reactions Author: Jim Faed Effective Date: 26/08/2014 Page 1 of 8 Authoriser: Peter Flanagan Previous ID: 111I01501 QA Approver: Meredith Smith REACTION/CAUSE SIGNS & SYMPTOMS PREVENTION MANAGEMENT Febrile (non haemolytic) transfusion Reaction (FNHTR) Frequency: 1-3:100 (higher in multi transfused recipients) Common Onset during or within 4 hours following transfusion Reaction induced by cytokines Other causes may exist Mild: unexplained fever 38 C and a temperature rise of at least 1 C but < C from pre- transfusion baseline, occurring in the absence of chills, rigors, respiratory distress and haemodynamic instability Moderate: unexplained fever 38 C and a temperature rise of at least 1 C but not meeting criteria for either mild or severe FNHTR Severe: unexplained fever >39 C and a temperature rise C from pre- transfusion baseline and chills/rigors Associated or secondary symptoms may be present: tachycardia, headache, nausea, flushing, anxiety, hypertension or occasionally hypotension In severe cases: marked apprehension, loin pain, and/or angina Check for history of previous transfusion reactions .

national 111i01502 guidelines for management of adverse transfusion reactions page 3 of 8 reaction/cause signs & symptoms prevention management

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