Transcription of 糖化ヘモグロビン（HbA1c）自動免疫測定試薬の開発
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糖化ヘモグロビン（HbA1c）自動免疫測定試薬の開発
71. HbA1c . AIA G .. ST AIA PACK HbA1c . 1.. HbA1c Hb . 2 non enzymatic . 2.. HbA1c . N . HbA1c Schiff base 2 .. HbA1c . 2 2 HbA1c . HbA1c HbA1c HbA1c . HbA1c 100 120 . 1 4 . 1 2 HbA1c . HbA1c HbA1c Total Hb HbA1c . Total Hemoglobin HbA1c HbA1c . HbA1c .. HbA1c .. 40 20. 5 . 12 .. 2 4,600 .. 37 10 . 1 HPLC HbA1c . HbA1c B F . HLC 723 4 4 MUP . 4 . 2300 4MU . ADA American Diabetes . Association HbA1c HbA1c . HbA1c HbA1c . HbA1c HbA1c . HPLC HbA1c .. AIA 360 AIA 600II HbA1c B F . 71 . 72 TOSOH Research Technology Review 2008 . Free .. Bound Hb . B F A1c HbA1c . 4 MUP .. 4MU . HbA1c . 6 . 18 . 50 . 20 . AIA . HbA1c . 3. AIA .. HPLC . 4.. HLC 723G7 . G7 Variant 1 . NGSP 3. National Glycohemoglobin Standardization Program EDTA 3 . Low Middle High 1 . 20 . HbA1c . coefficient of variation CV . AIA 20 90 4 .. CV .. Coefficient Sample Mean Pooled SD of Variation HbA1c . HWB Low HWB Middle . HWB High .. S . 6 Glu Val13 C 6 Coefficient 14 Sample Mean Pooled SD of Variation Glu Lys E 26.
（2）検量線と最小検出感度 HbA1c標準品（6濃度）を測定し作成した検量線 （検量範囲は2.0～16.0％）を図2に示した。
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