Transcription of Herceptest™ Interpretation Manual - Breast Cancer
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Herceptest™ Interpretation Manual - Breast Cancer
HercepTestTMInterpretation Manual Breast CancerEDUCATIONH ercepTestTMTable of Contents EDUCATION 5 Introduction6 HER2 Overview 6 HER2 Protein and HER2 Family 6 HER2 Testing IHC and FISH 7 HER2 Testing Algorithm 8 The HercepTestTM Kit9 HER2 IQFISH pharmDxTM Kit 9 Hybridizer Instrument for In Situ Hybridization (FISH)10 Checklist10 HercepTestTM Training Checklist11 Recommendations11 Recommended Data Tracking for HercepTestTM Immunostaining12 Technical Considerations12 Technical Considerations for Optimal HercepTestTM Performance12 Protocol Recommendations13 Tissue Processing Considerations13 Tissue Processing Recommendations14 Guidelines14 Review of HercepTestTM Scoring Guidelines14 Validation of the Assay15 Interpretation Guide for 1+ Cell Line16 Guidelines for Scoring17 Interpretation 17 Recommendations for Interpretation of HercepTestTM Breast Cancer 17 Steps for HercepTestTM Interpretation19 Staining Patterns24 Artifacts 24 I
for evaluating slides stained with HercepTestTM. ... NCCN Task Force Report and Recommendations: Journal of the National Comprehensive Cancer Network July 2005. | Edith A. Perez, Vera J. Suman, et al. HER2 Testing by Local, Central and Reference Laboratories in
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