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High Aspect Ratio Nanomaterials Enable …

1 High Aspect Ratio Nanomaterials Enable Biomolecule Delivery and Transgene Expression or Silencing in Mature Plants Gozde S. Demirer1, Huan Zhang1, Juliana L. Matos2,3, Roger Chang1, Linda Chio1, Brian Staskawicz2,3 and Markita P. Landry1,4,5* 1 Department of Chemical and Biomolecular Engineering, University of California, Berkeley, CA 94720, USA. 2 Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA. 3 Innovative Genomics Institute (IGI), Berkeley, CA 94720, USA. 4 California Institute for Quantitative Biosciences, QB3, University of California, Berkeley, CA 94720, USA. 5 Chan-Zuckerberg Biohub, San Francisco, CA 94158, USA.

6 Methods). Post-infiltration, DNA-CNTs traverse the plant cell wall and membrane to enter the cytosol. In the cytosol, we postulate that either the DNA-CNT complex further transports across

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