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HIGHLIGHTS OF PRESCRIBING INFORMATION - TYSABRI

Multiple Sclerosis (MS) TYSABRI is indicated as monotherapy for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults. TYSABRI increases the risk of PML [See Warnings and Precautions (5.1)]. When initiating and continuing ...

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DOSAGE AND ADMINISTRATION ---------------

www.tysabri.com

TYSABRI (natalizumab) injection, for intravenous use Initial U.S. Approval: 2004 WARNING: PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY See full prescribing information for complete boxed warning • TYSABRI increases the risk of progressive multifocal leukoencephalopathy (PML), an opportunistic viral infection of the brain

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