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IMPORTANT DRUG WARNING - Clozapine REMS

IMPORTANT drug WARNING Regarding Clozapine -Containing Products Indications and IMPORTANT Selected Safety Information About Clozapine -Containing Products INDICATIONS: Clozapine is an atypical antipsychotic indicated for: Treatment-resistant schizophrenia. Reducing suicidal behavior in patients with schizophrenia or schizoaffective disorder. CONTRAINDICATIONS: Known serious hypersensitivity to Clozapine or any other component of Clozapine . WARNING : SEVERE NEUTROPENIA; ORTHOSTATIC HYPOTENSION, BRADYCARDIA, AND SYNCOPE; SEIZURE; MYOCARDITIS AND CARDIOMYOPATHY; INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS See full prescribing information for complete boxed WARNING .

IMPORTANT DRUG WARNING Regarding Clozapine-Containing Products Indications and Important Selected Safety Information About Clozapine-Containing Products

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  Drug, Important, Warnings, Clozapine, Important drug warning

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