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Ingenuity Pathway Analysis (IPA

Sample to InsightIngenuity Pathway Analysis (IPA )For the Analysis and interpretation of omics dataIPA is a web-based software application for the Analysis , integration, and interpretation of data derived from omics experiments, such as RNAseq, small RNAseq, microarrays including miRNA and SNP, metabolomics, proteomics, and small scale experiments that generate gene and chemi-cal lists. Powerful Analysis and search tools uncover the significance of data and identify new targets or candidate biomarkers within the context of biological goes beyond Pathway Analysis by: Identifying key regulators and activity to explain expression patterns Predicting downstream effects on biological and dis-ease processes Providing targeted data on genes, proteins, chemicals, and dru

Ingenuity Pathway Analysis (IPA) is intended for molecular biology applications. This product is not intended for the diagnosis, prevention or treatment of a disease. For up-to-date licensing informa-tion and product-specific disclaimers, see the …

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Ingenuity Upstream Regulator Analysis in IPA®

pages.ingenuity.com

6 and the z‐score statistic is given by: V L T ê ë L Ü T Ü Ü 6 This latter formula is used in IPA to compute the activation z‐score of the transcriptional regulator. USING THE ACTIVATION Z‐SCORE TO INDEPENDENTLY CALL UPSTREAM REGULATORS Using the activation z‐score to identify upstream regulators independent of the overlap p‐value is based on the

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