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INOTROPE LEARNING PACKAGE

INOTROPE LEARNING PACKAGE LIVERPOOL ICU Sharon-Ann Shunker 2014 INOTROPE LEARNING PACKAGE 2014 2 (CNC) ICU Liverpool Hospital CONTENTS 1. Cardiac Output and its determinants 2. Definition / Indications for inotropes p. 6 3. Shock: types, classification , pathophysiology 4. Inotropic drugs 5. Calculating drug doses 6. References 7. LEARNING activities 8. INOTROPE guidelines INOTROPE LEARNING PACKAGE 2014 3 (CNC) ICU Liverpool Hospital Cardiac output & its determinants CARDIAC OUTPUT ( ) Cardiac output Is the amount of blood ejected from the heart in litres/minute NORMAL CARDIAC OUTPUT = 4 - 8 L/min The determinants of cardiac output are: Heart Rate, and Stroke Volume The determinants of stroke volume are: Preload Afterload Contractility CARDI

one hour, as per the sepsis bundle guidelines). Culture to determine the causative organism. For blood pressure not responding to fluid therapy – commence inotropic support and administer infusion of vasopressors to maintain SBP and MAP and hence prevent organ ischemia and injury.

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