Transcription of INTERACTIONS BETWEEN ANTIHYPERTENSIVE AGENTS …
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INTERACTIONS BETWEEN ANTIHYPERTENSIVE AGENTS …
IntroductionThe vast majority of hypertensive patients is treatedwith ANTIHYPERTENSIVE drugs for many years. Othertherapeutic AGENTS are frequently used simultaneously,thus giving rise to the possibility of drug-drug interac-tions. The potential for drug-drug INTERACTIONS increas-es with rising age, since elderly patients receive largernumber of drugs, but also because the renal excretionof several therapeutic AGENTS is impaired in the elderly,as a result of diminishing kidney function (1, 2). Theinteractions BETWEEN ANTIHYPERTENSIVE drugs and othertherapeutic AGENTS will be discussed and summarizedin the present issue, after a brief general explanationof the various mechanisms underlying drug-drug inter-actions.
cussed in more detail in a forthcoming issue of this newsletter. Central nervous depressant effects of all drugs suppressing the activity of the central nervous
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