Transcription of International treatment guidelines for anaemia in …
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International treatment guidelines for anaemia in …
Editorials International treatment guidelines for anaemia in chronic kidney disease . what has changed? Balancing the risks and benefits of erythropoietin-stimulating agents and iron therapy O. Robert J MacGinley ne in nine Australians has chronic kidney dis- evaluate the outcomes of higher versus lower haemo- MB BS, FRACP, Nephrologist and ease (CKD),1 although the condition may often globin targets, using recombinant human erythropoietin, Convenor of Medicine 1 not be recognised in primary There are found the unexpected reverse outcome of negative Rowan G Walker five stages of CKD, ranging from Stage 1, in which effects (increased cardiovascular events and mortality) in MD, FRACP, MPH, Director and Professor 2 patients have normal renal function but urinary abnor- patients randomly assigned to the higher ,9. malities, structural abnormalities or genetic traits point- The evidence now seems to suggest that haemoglobin 1 Deakin Medical School, ing to kidney disease, through to Stage 5, in which target levels between 100 and 115 g/L should be the aim Geelong, VIC.
Editorials MJA 199 (2) · 22 July 2013 85 The KDIGO guideline also covers the use of red cell transfusion in patients with CKD,5 again emphasising the importance of balancing risks and benefits.
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