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Introduction – Mendelian inheritance

Introduction Mendelian inheritance Genetics 371B Lecture 1 27 Sept. 1999. The mechanism of inheritance . Some early hypotheses: Predetermination , the homunculus theory Blending of traits Introducing a more systematic approach . Gregor Mendel (1822 1884) and his experiments with garden pea But first: Choosing a model organism What is it? Why bother? Features of a good model organism: Some commonly used model organisms: Mendel's organism of choice: garden pea His question: If a pair of plant lines showing a clear character difference are crossed, will the progeny show an intermediate phenotype? He established true-breeding lines . that showed character differences Made crosses (matings) between each pair of lines Example: Character: Phenotypes: x F1 . F1 x F1. F2 . Mendelian Genetics Monohybrid cross Genetics 371B Lecture 2 28 Sept. 1999. Interpreting Mendel's experiment Parents: Gametes: F1 progeny: Gametes: F2 progeny: Conclusions: 1.

Introduction – Mendelian inheritance Genetics 371B Lecture 1 27 Sept. 1999 The mechanism of inheritance… Some early hypotheses: Predetermination e.g., the homunculus theory Blending of traits Introducing a more systematic approach…

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