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INTRODUCTION TO HORMONES

INTRODUCTION TO HORMONES & HORMONAL CONTROLUNIVERSITY OF PNGSCHOOL OF MEDICINE AND HEALTH SCIENCES DISCIPLINE OF BIOCHEMISTRY & MOLECULAR BIOLOGYBMLS II / B Pharm II / BDS IIVJ Temple1 What are HORMONES ? Cells in multi-cellular organisms communicate with one another to coordinate their growth and metabolism; Cell to cell communicate is mainly via Extracellular signaling molecules or HORMONES ; Hormonescarry information from Sensor Cells, that sense changes in the environment, to Target Cellsthat respond to the changes; HORMONES tend to coordinate various metabolic processes in the body; 2 How are HORMONES classified?

What form of Thyroid hormone is biologically active? •T 3 is biological active form of Thyroid Hormones, •T 3 binds to receptors and triggers the end-organ effects of Thyroid Hormones, •Unbound or “Free” T 3 (F T 3) is important for the biological effects of Thyroid Hormones, including the feedback to the Pituitary and Hypothalamus, 33

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