Transcription of Introduction to Molecular Genetics and Genomics
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Introduction to Molecular Genetics and Genomics
CHAPTERI ntroduction to MolecularGenetics andGenomics11 Inherited traits are affected by genes. Genes are composed of the chemical deoxyribonucleic acid(DNA). DNA replicates to form copies of itself that are identical(except for rare mutations). DNA contains a genetic code specifying what types ofenzymes and other proteins are made in cells . DNA occasionally mutates, and the mutant forms specifyaltered proteins that have reduced activity or stability. A mutant enzyme is an inborn error of metabolism thatblocks one step in a biochemical pathway for the metabolismof small molecules. Traits are affected by environment as well as by genes. Organisms change genetically through generations in theprocess of biological MadnessAlfred D. Hershey and Martha Chase 1952 Independent Functions of Viral Protein and Nucleic Acid in Growth of BacteriophageThe Black Urine DiseaseArchibald E.
each daughter cell formed by cell division 2 Chapter 1 Introduction to Molecular Genetics and Genomics. receives an identical complement of chro-mosomes (Chapter 4). Further evidence for the importance of chromosomes was pro- ... Culture of R cells R colonies and a few S colonies
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