Transcription of Introduction to Pharmacodynamics
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Introduction to Pharmacodynamics
chapter . Introduction to Pharmacodynamics Reza Karimi 6. 1. Understand the physiology behind the gastrointestinal tract and the route of oral drug administration and Objectives physiological influences on Pharmacodynamics . 2. Understand the dynamics and functions of the major signal transduction systems and their different biomedi- cal and biological responses in regard to receptor ligand interactions. 3. Learn about the dynamics and mathematical expressions behind receptor ligand interactions. 4. Understand dose response relationships and factors that affect a pharmacological response. 5. Learn about agonistic, antagonistic, and partial agonistic binding of drugs to receptors.
In this chapter, an introduction to physiology of homeostasis and the gastrointestinal (GI) tract is provided to lay the groundwork for appreciating how different factors affect the role of pharmacodynamics in oral absorption of drugs.
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