Transcription of 甲状腺眼症診療の手引き - j-endo.jp
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甲状腺眼症診療の手引き - j-endo.jp
Digest .. 1.. 2.. 2011 9 . 1 .. 2018 3 2018 2 . 2020 6 . Digest . PDF .. 3.. QOL . MRI .. Clinical Question . CQ1 . 4.. quality of life (QOL) .. Graefe .. IgG4 . MALT MALT lymphoma . extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue type pyocele mucocele - .. Graves' ophthalmopathy GO . Graves' orbitopathy GO Thyroid-associated ophthalmopathy TAO Thyroid eye disease (TED) Dysthyroid ophthalmopathy (DO) Dysthyroid orbitopathy (DO) .. M ller .. TSH .. 5. Euthyroid Graves' disease hypothyroid Graves' disease . euthyroid Graves'. disease hypothyroid Graves' disease TRAb TSAb .. Occult thyroid eye disease . magnetic resonance imaging (MRI) .. TSH insulin like growth factor 1 (IGF-1) . TSH CTLA-4 PTPN22 CD40 T. regulatory T cells (Treg) Forkhead box P3 (FOXP3) . CD34+ TSH . TSH interleukin (IL)-6 IL-8 tumor necrosis factor (TNF)- . CD34- IGF-1 IGF-1 . IL-16 RANTES IL-1 prostaglandin e2 . T CD90+ transforming growth factor(TGF)- myofibroblast.
体抗体の作用を受けて、IL-16、RANTES、IL-1 、prostaglandin E2、長鎖のヒアルロン酸を産 生し、T 細胞の眼窩組織への遊走を促す。CD90+眼窩線維芽細胞はtransforming growth factor(TGF)- の作用でmyofibroblast へ分化し、外眼筋の線維化に寄与する。 2）病態
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