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重症心不全に対する集学的治療 - jsao.org

49 .. Yoshiki SAWA.. 1.. New York Heart Association NYHA . 1967 Barnard peak VO2. 1980 cyclosporine CyA 14 ml/kg/min Heart Failure Survival Score . quality of life QOL 2 .. 1997 Lower-Shumway . 1 Bicaval anastomosis 1 . Bicaval anastomosis .. 2.. 1 .. 4 . cardioplegia .. 565-0871 2-2 . E-mail.. 41 1 2012 31. (a) (b). 2 . 1 . a Lower-Shumway b Bicaval anastomosis . 3 2 . 40 .. 3. 30 .. 2010 7 . CyA tacrolimus Tac mycophenolate . mofetil MMF prednisolone Pre 3 . mammalian target of rapamycin . mTOR 1999 1 30 . 24 . CyA Tac 6 25 . LVAD . 868 376 LVAD 552 412 .. primary graft dysfunction 6 . 2 IABP . PCPS . modified Euro-Collins Celsior .. mTOR . CNI . PTCA 3 CNI . CyA Tac . 1 CyA . 5 3 . 1 3 . 1 . CD20 . 2010 7 1 .. 32 41 1 2012 . 1 30 5 70 . 4 BSA . mTOR m2 . QOL . CD25 mTOR CNI Novacor LVAS . DCM . 2 VAD . 30 2 3 4 1 11 BTT . 1 11 3 6 . 70 80 . 22 LVAS . QOL .. LVAS .. / . LVAS . 4.. bridge to eligibility . 1970 3 VAD.

32 人工臓器41巻1号 2012年 本格的な移植医療が始まった(図2)。しかし,40年以上も 遅れて始まった我が国の移植医療は前途多難であり,今後,

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Transcription of 重症心不全に対する集学的治療 - jsao.org