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Key recommendations for clinical practice

Emergency treatment of anaphylaxis | May 2021 Key recommendations for clinical practice Anaphylaxis is a potentially life-threatening allergic reaction. Recognise anaphylaxis based on:osudden onset and rapid progression of symptomsoAirway and/or Breathing and/or Circulation problemsoskin and/or mucosal changes (flushing, urticaria, angioedema) but these may be absent in up to 20% of diagnosis is supported if a patient has been exposed to an allergen known to affect them. Treat life-threatening features, using the Airway, Breathing, Circulation,Disability, Exposure (ABCDE) approach.

Antihistamines are considered a third-line intervention and should not be used to treat A irway/ B reathing/ C irculation problems during initial emergency treatment. o Non-sedating oral antihistamines, in preference to chlorphenamine,

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