Transcription of Latent Class Analysis - Harvard University
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Latent Class Analysis - Harvard University
Latent Class Analysis Karen Bandeen-Roche October 27, 2016. Objectives For you to leave here knowing . When is Latent Class Analysis (LCA) model useful? What is the LCA model its underlying assumptions? How are LCA parameters interpreted? How are LCA parameters commonly estimated? How is LCA fit adjudicated? What are considerations for identifiability / estimability? Motivating Example frailty of Older Adults the sixth age shifts into the lean and slipper'd pantaloon, with spectacles on nose and pouch on side, his youthful hose well sav'd, a world too wide, for his shrunk shank . -- Shakespeare, As You Like It . The frailty Construct Fried et al., J Gerontol 2001; Bandeen-Roche et al., J Gerontol, 2006. frailty as a Latent variable Underlying : status or degree of syndrome Surrogates : Fried et al. (2001) criteria weight loss above threshold low energy expenditure low walking speed weakness beyond threshold exhaustion part I: Model Latent Class model 1.
Frailty Y 1 Y m … ε m ε 1 η ... Part III: Evaluating Fit . ... – Goodness of fit df: 2M – J(M+1) P parameters (sum to 1) π parameters (M items*J classes) Bootstrapped Likelihood Ratio Test • In the absence of knowledge about theoretical distribution of difference in –2LL, can construct
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