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Lecture 3: Enzyme kinetics

Computational systems biology1 Lecture 3: Enzyme kineticsFri 19 Jan 2009 Computational Systems BiologyImages from: D. L. Nelson, Lehninger Principles of biochemistry , IV Edition, W. H. Freeman ed. A. Cornish-Bowden fundamentals of Enzyme kinetics , Portland Press, 2004A. Cornish-Bowden Enzyme kinetics , IRL Press, 1988computational systems biology2 Summary: Simple Enzyme kinetics Steady-state rate equations Reactions of two substrates Inhibition of Enzyme activity pH dependence Biological regulation of enzymescomputational systems biology3 Simple Enzyme Kineticscomputational systems biology4 Basics Enzyme kinetics studies the reaction rates of Enzyme -catalyzedreactions and how the rates are affected by changes in experimental conditions An essential feature of Enzyme -catalyzed reactions is saturation.

A. Cornish-Bowden Fundamentals of Enzyme Kinetics, Portland Press, 2004 A. Cornish-Bowden Enzyme Kinetics, IRL Press, 1988. computational systems biology 2 Summary: ... Nelson, Lehninger Principles of Biochemistry, IV Ed.,chapter 6. computational systems biology 13 Reactions of two substrates.

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