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Leflunomide - IPNSM

Leflunomide June 2017 Page 1 of 3 Using a printed guideline? Always check you are using the most up to date version. See Leflunomide Rheumatology shared care guideline. Specialist details Patient identifier Name: Location: Tel: Date: Introduction Licensed indications: active rheumatoid arthritis and active psoriatic arthritis in adults. Unlicensed indications: seronegative polyarthritis and vasculitis. Adult dosage and administration Dose: 10 - 20mg once daily. Leflunomide is available as: 10mg, 15mg and 20mg tablets. A 100mg tablet is also available for a three day loading dose referred to in product literature.

Leflunomide June 2017 Page 3 of 3 Adverse effects, precautions and contraindications Please note that leflunomide has a very long half life. Washout procedure with colestyramine is recommended in cases of significant drug toxicity (check SPC or BNF for further information).

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