Transcription of Linkage & Genetic Mapping in Eukaryotes
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Linkage & Genetic Mapping in Eukaryotes
11 Linkage & Genetic Mapping inLinkage & Genetic Mapping inEukaryotesEukaryotesCh. 6Ch. 622!!In eukaryotic species, each linearIn eukaryotic species, each linearchromosome contains a long piece of DNAchromosome contains a long piece of DNA A typical chromosome contains many hundredA typical chromosome contains many hundredor even a few thousand different genesor even a few thousand different genes!!The term Linkage has two related meaningsThe term Linkage has two related meanings 1. Two or more genes can be located on the1. Two or more genes can be located on thesame chromosomesame chromosome 2. Genes that are close together tend to be2. Genes that are close together tend to betransmitted as a unittransmitted as a unitCopyright The McGraw-Hill Companies, Inc. Permission required for reproduction or displayLINKAGE AND CROSSING OVERLINKAGE AND CROSSING OVER33!!Chromosomes are called Chromosomes are called Linkage groupslinkage groups They contain a group of genes that are linked togetherThey contain a group of genes that are linked together!
Genetic maps are useful in many ways: they Ð1. allow us to understand the overall complexity and genetic organization of a particular species Ð2. improve our understanding of the evolutionary relationships among different species Ð3. can be used to diagnose, and perhaps, someday to treat inherited human diseases
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