Transcription of Lipid Peroxidation: Chemical Mechanism, Biological ...
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Lipid Peroxidation: Chemical Mechanism, Biological ...
Chapter 1. Lipid Peroxidation: Chemical Mechanism, Biological implications and analytical determination Marisa Repetto, Jimena Semprine and Alberto Boveris Additional information is available at the end of the chapter 1. Introduction Currently, Lipid peroxidation is considered as the main molecular mechanisms involved in the oxidative damage to cell structures and in the toxicity process that lead to cell death. First, Lipid peroxidation was studied for food scientists as a mechanism for the damage to alimentary oils and fats, nevertheless other researchers considered that Lipid peroxidation was the consequence of toxic metabolites ( CCl4) that produced highly reactive species, disruption of the intracellular membranes and cellular damage (Dianzani & Barrera, 2008).
Lipid Peroxidation: Chemical Mechanism, Biological Implications and Analytical Determination 5 Reduced iron complexes (Fe2+) react with lipid peroxides (ROOH) to give alkoxy radicals, whereas oxidized iron complexes (Fe3+) react more slowly to produce peroxyl radicals.Both
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