Transcription of Localization in Epilepsy - amherst.edu
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Localization in Epilepsy - amherst.edu
Lo calization in Epilepsy Dimitris G. Placantonakis, MD, PhD, Theodore H. Schwartz, MD*. KEYWORDS. Epilepsy Electroencephalography MEG FMR1. PET SPECT. Pharmacologic therapy represents the first line of treatment of Epilepsy and is effec- tive in most patients. However, about 20% to 30% of cases develop intractable seizures that cannot be controlled by medication alone. In such cases, surgical inter- vention, including resection of epileptogenic brain tissue, is considered for thera- peutic, often curative, purposes. The concept of surgical management of Epilepsy relies on the premise of precise Localization of the epileptogenic focus, which gives rise to the seizures, and multiple techniques exist to identify epileptogenic tissue. However, to appreciate the value of each of these techniques, one must first gain an understanding of the organization of the epileptic focus, and a few terms must be defined.
Localization in Epilepsy DimitrisG.Placantonakis,MD, PhD, TheodoreH.Schwartz,MD* Pharmacologic therapy represents the first line of treatment of epilepsy and is effec-tive in most patients.
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