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Long-Term Follow-Up Guidelines

Long-Term Follow-Up Guidelinesfor Survivors of Childhood, Adolescent, and Young Adult CancersVersion - October 2018 Website: 2018 children s Oncology GroupAll rights reserved worldwideGenerously supported byWith special appreciation toJocelyn M. York, BA,Institute for Cancer Outcomes and SurvivorshipUniversity of Alabama at BirminghamBirmingham, AL for editing and typesettingLong-Term Follow-Up Guidelinesfor Survivors of Childhood, Adolescent, and Young Adult CancersVersion October 2018 children s Oncology GroupAll rights reserved worldwideCOG LTFU Guidelines Page v Version October 2018 Section #PageSexTherapeutic AgentPotential Late Effect1418 FemaleAlkylating AgentsReduced ovarian follicular pool1520 Alkylating AgentsAcute myeloid leukemia; Myelodysplasia1621 Alkylating AgentsPulmonary fi brosis1722 Alkylating AgentsCataracts1823 Alkylating AgentsUrinary tract toxicity1924 Alkylating AgentsBladder malignancy2025 Alkylating AgentsRenal toxicity2126 Heavy MetalsOtotoxicity2228 Heavy MetalsPeripheral sensory neuropathy2329 Heavy MetalsRenal toxicity2430 AntimetabolitesNeurocognitive defi cits2531 AntimetabolitesNo known late effects (cytarabine [low dose IV, IO, IT, SQ])2632 AntimetabolitesHepatic dysfunction; Sinusoidal obstruction sy

COG LTFU Guidelines – Page x Version 5.0 – October 2018 Abstract Release date: October 2018 Status: Updated from Version 4.0 incorporating modifi cations based on recommendations from the Children’s Oncology Group’s Long- Term Follow-Up Guideline Core Committee and its associated multidisciplinary Task Forces.

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