Transcription of Low-Substituted Hydroxypropyl Cellulose NF
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Low-Substituted Hydroxypropyl Cellulose NF
Low-Substituted Hydroxypropyl Cellulose NF. Functional Disintegrant CONTENTS PAGE 2. Introduction 3. Description 4. Manufacturing Process 6. Variety of grades 7. General properties 8. Interactions with water 9. Applications 11. Disintegration and Compressibility 12. Compatibility with active ingredients 13. Anti-capping 14. Direct compression 15. Wet Granulation (high speed mixer) 16. Wet Granulation (fluidized bed) 17. Pellet Extrusion 18. Formulation Examples 19. Bibliography 21. Product Specifications 22. INTRODUCTION 3. Introduction L-HPC ( Low-Substituted Hydroxypropyl Cellulose ) was first approved in 1977 as a disintegrant for pharmaceutical dosage forms in Japan. A recent survey shows that L-HPC is ranked as the first choice of tablet disintegrant by Japanese pharmaceutical companies. The key benefits of L-HPC include: Excellent compatibility with active ingredients Disintegration into smaller particles leading to better dissolution Anti-capping effect for tableting process.
INTRODUCTION 3 Introduction L-HPC (Low-Substituted Hydroxypropyl Cellulose) was first approved in 1977 as a disintegrant for pharmaceutical dosage forms in Japan. A recent survey shows that L-HPC is ranked as the first choice of tablet disintegrant by Japanese pharmaceutical companies.
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