Transcription of <233> ELEMENTAL IMPURITIES—PROCEDURES
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<233> ELEMENTAL IMPURITIES—PROCEDURES
Page 1 <233> ELEMENTAL impurities procedures INTRODUCTION This chapter describes analytical procedures for the evaluation of ELEMENTAL impurities that are suitable for the limits described in ELEMENTAL impurities Limits <232> and ELEMENTAL Contaminants in Dietary Supplements <2232>. Two procedures and criteria for the acceptability of alternative procedures are described.
Procedure 1 can be used for elemental impurities generally amenable to detection by inductively coupled plasma– atomic (optical) emission spectroscopy (ICP-AES or ICP-OES). Procedure 2 can be used for elemental impurities generally amenable to detection by inductively coupled plasma–mass spectrometry (ICP-MS).
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