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Mediation and interaction analysis Introduction ... - Stata

Mediation and interaction analysisIntroduction and overview of Stata commandsAndrea BellaviaUtrecht Exposome Hub, Utrecht UniversityDepartments of Environmental Health, Harvard Chan School of Public Stata Biostatistics and Epidemiology Virtual Symposium@andreabellaviaMediation analysisFebruary 18, 20211 / 22 Outline1. Principles of Mediation and pathway analysis2. Overview of current approaches and Stata Classical (Baron & Kenny) Structural Equation Modeling Counterfactual approach to Mediation General approach (Imai)3. Extensions and current gaps4. Themed4waycommand (Rino Bellocco)@andreabellaviaMediation analysisFebruary 18, 20212 / 221. Principles of Mediation and pathway analysisMediation and pathway analysis attempts to elucidate the mechanismsunderlaying an observedX is the association generated?

SEM in Stata The sem command allows conducting mediation analysis as long as both the dependent variable and the mediator variable are continuous variables (and all assumptions are met) The basic command is built on tting the two regression models presented before sem (M <- X C1 C2)(Y <- M X C1 C2)

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