Transcription of Mixing Insulins: 10 Units of Regular and 20 Units of …
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Mixing Insulins: 10 Units of Regular and 20 Units of …
490 unit IV / Responses to Altered Endocrine Function Lipodystrophy. Lipodystrophy (hypertrophy of subcuta- Lente insulin preparations may be mixed with each other;. neous tissue) or lipoatrophy (atrophy of subcutaneous tissue) Mixing with Regular insulin or with PZI and NPH insulin is may result if the same injection sites are used repeatedly, espe- not recommended. cially with pork and beef insulins. The tissues become hard- Do not mix human and animal insulins. ened and have an orange-peel appearance. The use of refriger- Always withdraw Regular insulin first to avoid contaminating ated insulin may trigger the development of tissue atrophy or the Regular insulin with intermediate-acting insulin . hypertrophy. These problems rarely occur with the use of hu- man insulins. Lipodystrophy and lipoatrophy alter insulin ab- insulin Regimens. The appropriate insulin dosage is indi- sorption, delaying its onset or retaining the insulin in the tissue vidualized by achieving a balance among insulin , diet, and ex- for a period of time instead of allowing it to be absorbed into ercise.
490 UNIT IV / Responses to Altered Endocrine Function Lipodystrophy. Lipodystrophy (hypertrophy of subcuta-neous tissue) or lipoatrophy (atrophy of subcutaneous tissue) may result if the same injection sites are used repeatedly, espe-
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