Monogenic(diabetes:( - NZSSD

Monogenic(diabetes:( A(guideline(for(NZ(h ealthcare(prac88oners(Phenotypes(for(com mon( monogenic (subtypes(Why(diagnose(MODY ,(MIDD(or(ND?( Isolated*mild* *hyperglycaemia* Small*increment*on*OGTT* Not*associated*with*micro*or*macrovascul ar* *even*in*the*absence*of*glucose*lowering * * Absence*of*family*history*is*common*as*d etected*only*incidentally*or*upon*screen ing* Progressive*beta*cell*failure*commonly*p resents*with*hyperglycemia*in*early*adul thood* *elevated*postAprandial*glucose,*with*la ter*elevated* *glucose*and*marked*excursion*on*OGTT*(> *mmol/l)* *to*sulphonylureas* *Gliclazide* Glycosuria*with*blood*glucose*<*10*mmol/ L* Elevated*HDL* Similar* *to*HNF1A,*but*with* *neonatal*hypoglycemia*or*macrosomia*eve n*without*maternal* diabetes * Maternally*inherited* diabetes *and*deafne ss*(MIDD)*and*maturity*onset* diabetes *of *the*young*(MODY)*subtypes*are*thought*t o*account*for*1A2%*of* diabetes *cases,*an d*are*frequently*mistaken*for*type*1*or* 2* diabetes *( *2000*cases*in*New*Zealand).)))))))))))) )))))))

Monogenic(diabetes:(A(guideline(for(NZ(healthcare(prac88oners(Procedure(and(costs(We(advise(consultant(diabetes(or(endocrinologist(review(for(all(molecular(gene8c ...

Loading..

Tags:

  Diabetes, Monogenic

Information

Related search queries