Transcription of Monte Carlo Methods and Importance Sampling
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Monte Carlo Methods and Importance Sampling
Lecture Notes for Stat 578Cc Eric C. AndersonStatistical Genetics20 October 1999(subbin' Thompson) Monte Carlo Methods and Importance SamplingHistory and de nition:The term \ Monte Carlo " was apparently rst used by Ulam and vonNeumann as a Los Alamos code word for the stochastic simulations they applied to building betteratomic bombs. Their Methods , involving the laws of chance, were aptly named after the inter-national gaming destination; the moniker stuck and soon after the War a wide range of stickyproblems yielded to the new techniques. Despite the widespread use of the Methods , and numerousdescriptions of them in articles and monographs, it is virtually impossible to nd a succint de ni-tion of \ Monte Carlo method" in the literature. Perhaps this is owing to the intuitive nature of thetopic which spawns many de nitions by way of speci c examples.
This can be computed exactly by multiplying transition probability matrices together, or by employing the Baum (1972) algorithm (which you will learn about later), but it can also be approximated by Monte Carlo. It is simple to simulate genetic drift in a Wright-Fisher population; thus we can easily simulate values for X tgiven X 0 = x 0. Then ...
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