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多発性硬化症(MS)は人生の開花 ... - amed.go.jp

16ek0109084h0002 .. I.. Practical Research Project for Rare/Intractable Diseases . Development of a new disease modifying drug for multiple sclerosis .. National Institute of Neuroscience, National Center of Neurology and Psychiatry, Director, Takashi Yamamura .. II.. MS . MS .. PML HPS . OCH . 1. Nature 413:531, 2001 STEP1 . OCH MS . STEP1 OCH .. STEP2 .. STEP2 . DNA OCH . MS OCH . MRI .. Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) that primarily affects young adults. The prevalence of MS is rapidly increasing in Japan. Although several disease-modifying drugs for MS are available, current drugs for MS pose lots of burden for patients in terms of efficacy, side effects and adherence. OCH. is a synthetic alpha-GalCer analog which respond to human invariant NKT cells to exert immunomodulatory effects. The purpose of this study is to develop an oral drug OCH as a new disease-modifying therapy for MS.

1 (報告様式4) 【 16ek0109084h0002】 平成. 29年 5月 31日. 平成. 28. 年度 委託研究開発成果報告 書. I. 基本情報

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