Transcription of 経過 予後 - neurology-jp.org
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経過 予後 - neurology-jp.org
8 .. CQ.. 8 1 1.. 24 . 1 multiple sclerosis . MS .. MS McDonald . MS primary progressive MS PPMS . MS .. McDonald 1 3 . 24 .. Uhthoff s phenomenon .. MS .. 24 .. 30 . 30 . MS 1 . visual evoked potential VEP . 114 I 8 . MRI .. MS 4 MS activity . MRI Gd . T2 MS relapsing remitting MS RRMS . MRI RRMS not active . progression McDonald 1 3 . PPMS 1 . MRI . RRMS MS secondary progressive MS SPMS SPMS . MS 4 . MS .. 1 PPMS. 1 PPMS not progressing . progressing . worsening .. 1 McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis guidelines from the international panel on the diagnosis of multiple sclerosis. Ann Neurol. 2001 50 1 121 127. 2 Polman CH, Reingold SC, Edan G, et al. Diagnostic Criteria for Multiple Sclerosis 2005 Revisions to the McDonald Criteria . Ann Neurol. 2005 58 6 840 846. 3 Polman CH, Reingold SC, Banwell B, et al. Diagnostic Criteria for Multiple Sclerosis 2010 Revisions to the McDonald Criteria . Ann Neurol. 2011 69 2 292 302.
発症後10 年でKurtzke 総合障害度スケール（Expanded Disability Status Scale of Kurtzke： EDSS）スコア3.0（2.0 または2.5 とするものもある）以下のMS をbenign MSと称し，MS の 20%前後でみられる． 解説・エビデンス 1. 自然経過からみた病型分類
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