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Neurosurgery is complex. DuraGen is the simple choice.

Neurosurgery is is the simple Closure Family of Grafts Dural Regeneration MatrixDuraGen Family of GraftsA Breakthrough in Dural RepairA Pioneer in Dural Regeneration Matrices The onlay nature of DuraGen revolutionized duraplasty. The highly porous collagen scaffold promotes the fibrin clot process to prevent CSF leakage while promoting natural dural growth. Integra pioneered regenerative medicine. Over 10 million collagen implants. Integra created the onlay dural graft paradigm. Conforms intimately to complex surfacesFor almost forty years, Integra and its predecessors have been leading the development and manufacturing of collagen implants and advanced regenerative technologies. In the early 1970 s the first collagen matrix to improve skin restoration of severely burned patients was developed. This advanced matrix led to a revolution in understanding the science behind the biological response and role of extracellular matrices in tissue regeneration.

• Type 1 collagen matrix rapidly initiates platelet aggregation. • Upon contact with the collagen matrix, platelets degranulate and release clotting factors that initiate fibrin clot formation. • The fibrin clot creates a watertight barrier and binds the ... ® is the simple choice.

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  Simple, Choice, Complex, Aggregation, Neurosurgery, Neurosurgery is complex, Duragen is the simple choice, Duragen

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