Transcription of New CLSI Coagulation Guidelines: 2009 Update
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New CLSI Coagulation Guidelines: 2009 UpdateDorothy M. (Adcock) Funk MDMedical Director, Esoterix Coagulation MAYO/NASCOLA Quality ConferenceApril 2009 Disclosures NoneProgram Objectives Bring awareness of recently published Coagulation focused CLSI guidelines and those guidelines currently being drafted Highlight the important features of two recently published guidelinesCLSI: Coagulation -focused Guidelines Four guidelines recently publishedzPre-analytical variableszCoagulometer evaluation protocolzPT/APTT testingzPT/INR calibration published 2005zPlatelet function testing Two guidelines currently in processzQuantitative D-dimerzVon Willebrand Factor Antigen and Activity CLSI Document H21-A5 Collection, Transport, and Processing of Blood Specimens for Testing Plasma-Based Coagulation Assays and Molecular Hemostasis Assays; Approved Guideline Fifth Edition Dorothy M.
CLSI Document H47-A2 • Factor Sensitivity (Responsiveness) z Level of factor activity at which the APTT (or PT) test result rises above the upper limit of the established reference
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