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Nitroreductases: Enzymes with Environmental ...

nitroreductases : Enzymes with Environmental , biotechnological and clinical importance Iuri Marques de Oliveira1, Diego Bonatto1,2 and Jo o Antonio P gas Henriques*1,2 1 Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Gon alves 9500, 91507-970 Porto Alegre, RS, Brazil 2 Instituto de Biotecnologia, Universidade de Caxias do Sul (UCS), Rua Francisco Get lio Vargas 1130, Bloco 57, 95070-560 Caxias do Sul, RS, Brazil. *Corresponding author: e-mail: p Telephone: 55-51-3308-7602; Fax: 55-51-3308-6084 The nitroreductase family comprises a group of flavin mononucleotide (FMN)- or flavin adenine dinucleotide (FAD) -dependent Enzymes that are able to metabolize nitroaromatic and nitroheterocyclic derivatives (nitrosubstituted compounds) using the reducing power of nicotinamide adenine dinucleotide (NAD(P)H).

Nitroreductases: Enzymes with Environmental, Biotechnological and Clinical Importance Iuri Marques de Oliveira1, Diego Bonatto1,2 and João Antonio Pêgas Henriques*1,2 1Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Gonçalves 9500, 91507-970 Porto Alegre, RS, Brazil 2Instituto de …

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