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World Gastroenterology Organisation, 2012 World Gastroenterology Organisation Global Guidelines Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis June 2012 Review Team Douglas LaBrecque (chair) USA Zaigham Abbas Pakistan Frank Anania USA Peter Ferenci Austria Aamir Ghafoor Khan Pakistan Khean-Lee Goh Malaysia Saeed S. Hamid Pakistan Vasily Isakov Russia Maribel Lizarzabal Venezuela Manuel Mojica Pernaranda Colombia Juan Francisco Rivera Ramos Mexico Shiv Sarin India Davor timac Croatia Alan Thomson Canada Muhammed Umar Pakistan Justus Krabshuis France Anton LeMair Netherlands WGO Global Guidelines NAFLD/NASH (long version) 2 World Gastroenterology Organisation, 2012 Contents 1 Introduction 3 2 Epidemiology 5 3 Pathogenesis and risk factors 8 4 Diagnosis 11 5 Management 18 6 Summary 22 References 23 List of tables Table 1 Mortality in NAFLD/NASH 3 Table 2 Clinical identification of the metabolic syndrome 4 Table 3 Regional obesity/overweight data (representative examples)
NASH represents the most severe histologic form of nonalcoholic fatty liver disease (NAFLD), which is defined by fat accumulation in the liver exceeding 5% of its weight.
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