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OCT in Glaucoma

June 2007 Rajiv Sukumaran et al. - Cyclosporine183 OCT in GlaucomaDr. Valsa Stephen MS DO DNB, Dr. Arup Chakrabarti MS DO, Dr. Sonia Rani John DNB,Dr. Meena Chakrabarti MS DO DNBG laucoma is the clinical manifestation of irreversibledamage to the retinal ganglion cells resulting in retinalnerve fibre layer loss. This becomes functionally evidentas visual field loss which is detected on perimetry. It isnow known that structural damage detected by RNFL defects precedes functional loss. 40 % axonal loss hasto occur before any detectable change occurs in visualfunction. 1 Another study 2 showed that RNFL loss wasdetected nearly six years before visual field defectsoccurred in ocular hypertensives.

June 2007 Valsa Stephen et al. - OCT in Glaucoma 185 ANALYSIS PROTOCOLS FOR GLAUCOMA (Fig. 2 & 3) 1. RNFL Thickness (Single Eye) The normal RNFL graphs appear as a “double hump” :

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