Transcription of OECD/OCDE 414
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OECD/OCDE 414
OECD/OCDE414 Adopted:22ndJanuary 20011/11 OECD GUIDELINE FOR THE TESTING OF CHEMICALSPROPOSAL FOR UPDATING GUIDELINE 414 Prenatal developmental Toxicity Copenhagen in June 1995, an OECD Working Group on Reproduction and DevelopmentalToxicity discussed the need to update existing OECD Test Guidelines for reproduction and developmentaltoxicity and the development of new Guidelines for endpoints not yet Working Grouprecommended that the Guideline for developmental Toxicity should be revised, based on a proposal receivedfrom the US (1). The Working Group reached agreement on all major elements of the revised version of guideline for developmental toxicity testing is designed to provide general informationconcerning the effects of prenatal exposure on the pregnant test animal and on the developing organism; thismay include assessment of maternal effects as well as death, structural abnormalities, or altered growth in t
OECD/OCDE 414 Adopted: 22nd January 2001 1/11 OECD GUIDELINE FOR THE TESTING OF CHEMICALS PROPOSAL FOR UPDATING GUIDELINE 414 Prenatal Developmental Toxicity Study INTRODUCTION
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