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Operational Qualification/ Performance Qualification for ...

Operational Qualification / Performance Qualification for hplc Instruments Operating Instructions Version: Date: Oktober 2008 2008 DIONEX Doc.: OQ and PQ Operating Instructions OQ and PQ Operating Instructions Table of Contents 1 How to Use this Manual ..1 2 Defining the Limits ..3 Operational Qualification (OQ) ..3 Performance Qualification (PQ) ..3 System Suitability Check (SSC; also: System Suitability Test, SST)..3 Basic Requirements for Successful OQ and PQ ..4 Overview of the UV Detectors Using Analytical Flow UV Detectors Using Non-Analytical Flow 11 Autosamplers .. 13 Pumps .. 18 Thermostatted Column Compartments and Column Ovens .. 22 Fluorescence Detectors .. 24 Refractive Index Detectors .. 25 Evaporative Light Scattering 25 3 General Test 27 Test Procedure for Single Wavelength and VWD-3400RS Detectors .. 29 Connecting and Configuring the System.

HPLC_OQ_PQ_E_Manual.doc – Version: 6.8 dated Oktober 2008 Contents: III of IV OQ and PQ Operating Instructions Contents: IV of IV HPLC_OQ_PQ_E_Manual.doc – …

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