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Optimize Peak Detection & Integration with ApexTrack ...
2011 Waters Corporation1 Noise and Drift CalculationsManaging Manually Integrated resultsSystem SuitabilityOptimize peak Detection & Integration with ApexTrack /Processing TheoryRune Buhl Frederiksen, Nordic Customer Education Manager 2011 Waters Corporation2 Presentation overview of Integration Theory Noise & Drift Calculations Managing Manually Integrated Results in a Result Set System Suitability Calculations and Limits Exercise 2011 Waters Corporation3 Integration requires three operations:1. Find the peak ( peak Detection )2. Find the baseline of the peak3. Compute the peak s area and height The first two are the challenge Empower has two different algorithms to perform Integration Traditional Apex TrackIntegration 2011 Waters Corporation4 Traditional Integration peak Width and Threshold work together to detect the peaks from the Global Parameters peak Width Threshold Minimum Area Minimum Height Traditional Integration4 Global Parameters 2011 Waters Corporation5 peak Width peak width is measured at the baseline of the narrowest peak of interest and is used to determine a bunching factor.
©2011 Waters Corporation 3 Integration requires three operations: 1. Find the peak (peak detection) 2. Find the baseline of the peak 3. Compute the peak’s area and height
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