Transcription of ORENCIA U.S. Prescribing Information
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ORENCIA U.S. Prescribing Information
HIGHLIGHTS OF Prescribing Information Subcutaneous Administration for Adult PsA ( ). These highlights do not include all the Information needed to use ORENCIA safely Administer by subcutaneous injection once weekly without the need of an and effectively. See full Prescribing Information for ORENCIA . intravenous loading dose. ORENCIA (abatacept) for injection, for intravenous use Patients transitioning from ORENCIA (abatacept) intravenous therapy to ORENCIA (abatacept) injection, for subcutaneous use subcutaneous administration should administer the first subcutaneous dose instead Initial Approval: 2005 of the next scheduled intravenous dose. ----------------------------- RECENT MAJOR CHANGES------------------------------ General Dosing Information for Intravenous Administration ( and ). Indications and Usage, Juvenile Idiopathic Arthritis ( ) 3/2017 Administer as a 30-minute intravenous infusion ( , ).
Reconstitute ORENCIA lyophilized powder and administer after dilution [see Dosage and Administration (2.5)] as a 30-minute intravenous infusion utilizing the weight range-based dosing specified in Table 1. Following the initial intravenous infusion, administer as an intravenous infusion at 2 and 4 weeks and every 4 weeks thereafter.
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