Transcription of Oxygen Saturation: A Guide to Laboratory …
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Oxygen Saturation: A Guide to Laboratory …
10 CLINICAL Laboratory NEWS FEBRUARY 2006 CLN SLAB 2006:SUPPORTING CLINICALDECISIONSSERIESThe Clinical Laboratory Standards In-stitute (CLSI) defines O2sat as an estimated value based on a calculation, whereas SaO2and SpO2 refer to the arterial saturation measured spectrophotometrically. (To avoid further confusion, I will use only O2sat and SO2 for the remainder of this article.) CO-oximetry, a more complex and reliable method, measures the concentration of he-moglobin derivatives in the blood, the results of which are then used to calculate various parameters such as hemoglobin derivative fractions ( , FO2Hb), total hemoglobin, and Oxygen most patients, the results O2sat, SO2, and FO2Hb from these three methods are virtually identical. But in cases of dyshemo-globinemia, some methods can yield mis-leading results, so health care professionals need to understand the differences between these methods and the limitations of each.
2006 CLN / Oxygen Saturation Oxygen saturation Sa S
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