Transcription of Pathophysiology of Gallstone Formation and …
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Of Gallstone Formation and PancreatitisRobert F. secretions and bile are required for digestion Bile: Emulsification of fat Pancreatic secretions: -Digestion of proteins, carbohydrates and fat-Neutralization of the acidic Secreted by hepatocytes- Transported through the biliary system- Stored and concentrated in the gallbladder- Released into duodenum after ingestionof food (mediated by CCK) compositionMiscellaneous (Pigment, Protein)CholesterolBile SaltsPhospholipids(Lecithin) salts are conjugated with glycine or taurine to increase their solubility at lower pHDehydroxylationDehydroxylationPrimary bile saltsSecondary bile functions of bile1. Emulsification of fats in the intestine2. Cholesterol excretiona. Bile salts are generated from cholesterol and their synthesis thus decreases the cholesterol poolb.
2 S.N.S Bile - Secreted by hepatocytes - Transported through the biliary system - Stored and concentrated in the gallbladder - Released into duodenum after ingestion
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