Perioperative Anticoagulation Algorithm

SCHS Anticoagulation Guidelines 1 Perioperative Anticoagulation GUIDELINE/DOAC management Options for Anticoagulation continue to expand with the use of direct oral anticoagulants (DOACs). While the thromboembolic risk is determined by the patient s condition, the Perioperative management of DOACs is vastly different and varied. Bridging is not recommended with DOACs. DOAC Patient is Taking Surgery Bleeding Risk Preoperative DOAC Interruption Schedule Postoperative DOAC Resumption Schedule Day -5 Day -4 Day -3 Day -2 Day -1 Day +1 Day + 2 Day +3 Day +4 Apixaban (Eliquis) Mod/High X X X Low X Dabigatran (CrCl>50ml/min) Mod/High X X X Low X Dabigatran (CrCl<50ml/min) Mod/High X X X X X Low X X Rivaroxaban (Xarelto) Mod/High X X X Low X For patients undergoing neuraxial anesthesia, hold DOAC 72 hours prior to procedure.

References for anticoagulation and antiplatelet therapy management guidelines: Abualsaud AO, Eisenberg MJ. Perioperative management of patients with drug-eluting stents. J Am Coll Cardiol Interv, 2010; 3:131-142.

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  Management, Therapy, Anticoagulation, Therapy management

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