Transcription of Pharmaceutical Compounding and Dispensing Sample Chapter
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Pharmaceutical Compounding and Dispensing Sample Chapter
6 SolutionsIntroduction and overview101 General principles of solution preparation103 Solubility103 Stability103 General method103 Oral solutions104 Elixirs104 Linctuses105 Syrups105 Mixtures105 Draughts105 Spirits105 Paediatric drops105 Gargles and mouthwashes105 Enemas and douches105 External solutions105 Lotions105 Liniments105 Applications105 Collodions106 Worked examples106 Summary of essential principles relatingto solutions112 Packaging112 Discard dates112 Labelling113 Introduction and overviewSolutions are one of the oldest dosage forms used in thetreatment of patients and afford rapid and highabsorption of soluble medicinal products. Therefore,the Compounding of solutions retains an importantplace in therapeutics today. Owing to the simplicityand hence the speed of preparation of an ad hoc for-mulation, they are of particular use for individualswho have difficulty in swallowing solid dosage forms(for example paediatric, geriatric, intensive care andpsychiatric patients), where compliance needs to bechecked on administration (for example in prisons orpsychiatric pharmacy) and in cases w
* Some drugs are poorly soluble. The solubility of a drug needs to be taken into consideration when preparing a solution to ensure that the final volumeproducedisnotexcessive.Insomecasesit maybe necessary to alter the vehicle or drugform (for example the free alkaloid or its salt) in order
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