Transcription of PHARMACY UPDATE Antihistamine use in children
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PHARMACY UPDATE Antihistamine use in children
Downloaded from on June 9, 2015 - Published by PHARMACY UPDATE . Antihistamine use in children Roisin Fitzsimons,1,2 Lauri-Ann van der Poel,1 William Thornhill,3. George du Toit,1,2 Neil Shah,4,5 Helen A Brough1,2. AR in In the UK, the Phase 3. 1. children 's Allergy Service, Guy's ABSTRACT. and St. Thomas' NHS. This review provides an overview of the use of (2002 2003) ISAAC study found a Foundation Trust, London, UK. 2. Department of Asthma, Allergy antihistamines in children . We discuss types of prevalence of AR symptoms and and Respiratory Science, King's histamine receptors and their mechanism of 16% eczema symptoms in 6-year-old to College London, London, UK. 3. action, absorption, onset and duration of action 7-year-old Hospital admissions Evelina children 's PHARMACY , of first-generation and second-generation for food allergic reactions in the UK have Guy's and St. Thomas' NHS. Foundation Trust, London, UK H(1)-antihistamines, as well as elimination of increased by 500% between 1990 and 4.
Table 1 Summary of the more commonly used H(1)-antihistamines licensed for use in children First-generation H(1)-antihistamines The most common adverse effect of the first-generation H(1)-antihistamines is central nervous system depression, with effects varying from slight drowsiness to deep sleep.
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