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Polymorphism—A Critical Consideration in Pharmaceutical ...

Pharmaceutical F. Bauer]For more Author information, go to [Polymorphism A Critical Consideration in Pharmaceutical Development, Manufacturing, and StabilityWelcome to Pharmaceutical Solids. This column discusses scientific principles associated with Pharmaceutical solids useful to practitioners in validation and compliance. This column has been developed with the intention to help readers under-stands the principles associated with Pharmaceutical solids, and to be a useful resource for daily work applications.

rate, hygroscopicity, and others. • Polymorphs may interconvert depending on condi-tions. Usually the metastable kinetic form converts ... dissolving than the crystalline state, and has a variable solubility that is usually higher than the crystalline form.

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