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PREPARATION AND EVALUATION OF HERBAL GEL …
Mohsin of PharmaceuticalResearch &Education,2017, 1( 2), 201-224201 Research ArticleJournal of Pharmaceutical Research & EducationJournal homepage: AND EVALUATION OF HERBAL GEL FORMULATIONM ohsin J. Jamadar*,Rajmahammad Husen ShaikhDepartment of Quality Assurance,Pharmaceutics,Appasaheb Birnale College of pharmacy,Sangli. Maharashtra, India. :-Herbalmedicinesisstillthemainstayofabo ut75-80%oftheworld spopulation, mainlyindevelopingcountries,forprimaryhe althcarebecauseofbetterculturalacceptabi lity,better compatibilitywith human bodyand lesser side effects. Herbalmedicinesconsistofplantoritspartto treatinjuries,diseaseorillnessesandare the oldest form of healthcareknown to ,HPMCK100 MandXanthangumshowedgoodhomogeneity,nosk inirritation,goodstabilityandanti-inflam matoryactivity. However,theXanthangumbasedgelprovedtothe formulaofchoice,sinceitshowedthe highest percentage ofextrudability, good spreadabilityandrheological properties. FormulationF5with1%leavesextractandF11wi th1% F11shows approximatelyequal anti-inflammatoryactivity.
Formulation F5 with 1 % leaves extract and F11 with 1% root extract of Clerodendrum serratum showed the best formulation with significant anti-inflammatory activity. Formulation 5 and F11 shows approximately equal anti-inflammatory activity. Hence, there is no need to used roots for the preparation of medicines for anti-inflammatory action ...
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